106720-63-2Relevant articles and documents
Dihydropyrimidine Calcium Channel Blockers. 4. Basic 3-Substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic Acid Esters. Potent Antihypertensive Agents
Rovnyak, George C.,Atwal, Karnail S.,Hedberg, Anders,Kimball, David S.,Moreland, Suzanne,et al.
, p. 3254 - 3263 (1992)
We have examined a series of novel dihydropyrimidine calcium channel blockers that contain a basic group attached to either C5 or N3 of the heterocyclic ring.Structure-activity studies show that a 1-(phenylmethyl)-4-piperidinyl carbamate moiety at N3 and