1067233-93-5

Basic information

• Product Name: 3,4-dimethoxy entacapone
• Synonyms: 3,4-dimethoxy entacapone
• CAS NO: 1067233-93-5
• Molecular Weight: 333.344
• Mol File: 1067233-93-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,4-dimethoxy entacapone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxy entacapone(1067233-93-5)
• EPA Substance Registry System: 3,4-dimethoxy entacapone(1067233-93-5)

Safety Data

• Hazardous Substances Data: 1067233-93-5(Hazardous Substances Data)

Upstream product

• 91004-48-7 4,5-Dimethoxy-3-nitrobenzoic acid 
• 134610-30-3 3,4-dimethoxy-5-nitrobenzoyl chloride 

Downstream Products

• 130929-57-6 entacapone 

Relevant articles and documents

Efficient approach to pure entacapone and related compounds

A new and efficient process through a new intermediate, (2E)-2-cyano-3-(3,4-dihydroxy-5-nirtrophenyl)prop-2-enoic acid 15, has been described for preparing substantially pure entacapone 1. This new intermediate 15 was prepared by Knoevenagel condensation of 3,4-dihydroxy-5-nitrobenzaldehyde 2 with 2-cyanoacetic acid 14 and was further condensed with diethylamine to get pure entacapone 1. Some of the important process-related impurities of entacapone (17, 18, 19, and 20) were also prepared easily from this intermediate 15. Copyright Taylor & Francis Group, LLC.