1067975-40-9

Basic information

• Product Name: glycine tert-butyl ester, p-chlorobenzaldehyde Schiff base
• Synonyms: glycine tert-butyl ester, p-chlorobenzaldehyde Schiff base
• CAS NO: 1067975-40-9
• Molecular Weight: 253.729
• Mol File: 1067975-40-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: glycine tert-butyl ester, p-chlorobenzaldehyde Schiff base(CAS DataBase Reference)
• NIST Chemistry Reference: glycine tert-butyl ester, p-chlorobenzaldehyde Schiff base(1067975-40-9)
• EPA Substance Registry System: glycine tert-butyl ester, p-chlorobenzaldehyde Schiff base(1067975-40-9)

Safety Data

• Hazardous Substances Data: 1067975-40-9(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 27532-96-3 glycine tert-butyl ester hydrochloride 
• 6456-74-2 Glycine tert-butyl ester 

Downstream Products

• 1025891-46-6 (E)-(S)-2-{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-5-phenyl-pent-4-enoic acid tert-butyl ester 
• 1027219-92-6 C₁₇H₂₂ClNO₂ 
• 1025830-09-4 C₂₀H₂₁ClFNO₂ 
• 1025891-51-3 C₁₆H₂₀ClNO₂ 
• 1026227-92-8 C₂₁H₂₄ClNO₂ 
• 16874-17-2 L-phenylalanine tert-butyl ester 
• 199588-89-1 2-amino-pent-4-enoic acid tert-butyl ester 

Relevant articles and documents

Highly enantioselective monoalkylation of p-chlorobenzaldehyde imine of glycine tert-butyl ester under mild phase-transfer conditions

The selective monoalkylation of glycine tert-butyl ester aldimine Schiff base 3 has been realized in high chemical yield with excellent enantioselectivity under mild liquid-liquid phase-transfer conditions by the use of binaphthyl-derived chiral quaternar

PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF

Disclosed is a process for producing an asymmetric mono-substituted alkylated compound of an α-amino acid which is represented by a specific formula by using an aldimine-type Schiff base. In the process, the alkylation of an aldimine-type Schiff base in a medium in the presence of an optically active quaternary ammonium salt phase transfer catalyst and an inorganic base is started, and subsequently the reaction is quenched at any time preceding the completion of the stoichimetrical reaction, thereby yielding a mono-substituted alkylated product having a high optical purity.