1068652-80-1

Basic information

• Product Name: Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe
• Synonyms: Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe
• CAS NO: 1068652-80-1
• Molecular Weight: 760.974
• Mol File: 1068652-80-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe(1068652-80-1)
• EPA Substance Registry System: Boc-L-(?-Me)-His-AGly-L-Cha-L-Phe-OMe(1068652-80-1)

Safety Data

• Hazardous Substances Data: 1068652-80-1(Hazardous Substances Data)

Upstream product

• 61070-22-2 Boc-L-(?-Me)-His-OH 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 37462-62-7 Boc-Cha-OH * dicyclohexylamine 
• 37736-82-6 (S)-2-tert-butoxycarbonylamino-3-cyclohexylpropionic acid 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 67-56-1 methanol 

Relevant articles and documents

The Enantioselective Dakin-West Reaction

Here we report the development of the first enantioselective Dakin-West reaction, yielding α-acetamido methylketones with up to 58 % ee with good yields. Two of the obtained products were recrystallized once to achieve up to 84 % ee. The employed methylimidazole-containing oligopeptides catalyze both the acetylation of the azlactone intermediate and the terminal enantioselective decarboxylative protonation. We propose a dispersion-controlled reaction path that determines the asymmetric reprotonation of the intermediate enolate after the decarboxylation.

Enantiomerically enriched trans-diols from alkenes in one pot: A multicatalyst approach

Multicatalysts consisting of non-natural oligopeptides with distinctly different catalytic moieties create molecular complexity in a multistep one-pot sequence starting from simple alkenes yielding highly enantiomerically enriched trans-diols. The Royal Society of Chemistry 2012.