106989-73-5Relevant articles and documents
A three-component one-pot synthesis of penta-substituted pyrroles via ring opening of α-nitroepoxides
Zhao, Donghong,Zhu, Yue,Guo, Shanshan,Chen, Wenteng,Zhang, Guolin,Yu, Yongping
supporting information, p. 2872 - 2877 (2017/04/26)
A novel and facile one-pot reaction has been developed to synthesize a variety of penta-substituted pyrroles from α-nitroepoxides, primary amines and dialkyl acetylenedicarboxylates under the conditions without catalyst. Furthermore, the controlled experi
Titanium-mediated reductive cross-coupling reactions of imines with nitriles: An efficient route for the synthesis of α-aminoketones or 1,2-diketones
Chen, Haoyi,Fan, Guoqin,Li, Shi,Mao, Kebin,Liu, Yuanhong
supporting information, p. 1593 - 1596 (2014/03/21)
The reaction of imines with low-valent titanium species, generated in situ by using Ti(OiPr)4/2 c-C5H9MgCl reagent, affords titanium-imine complex, which can couple with nitriles to provide 2,5-diazatitanacyclop
A modular approach to the synthesis of 1,4,5-substituted-2-aminoimidazoles
Su, Zhaoming,Peng, Lingling,Melander, Christian
, p. 1204 - 1206 (2012/03/27)
Diversified 1,4,5-substituted-2-aminoimidazoles were rapidly assembled via sequential N-H insertion and Grignard addition to α-diazoesters. Lead compounds were identified as antibiotics against Gram-positive bacteria with an MIC value as low as 2 μg/mL.
