107059-12-1

Basic information

• Product Name: 2-ethoxy-1,2-diphenylethanol
• Synonyms: 2-ethoxy-1,2-diphenylethanol
• CAS NO: 107059-12-1
• Molecular Weight: 242.318
• Mol File: 107059-12-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-ethoxy-1,2-diphenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-1,2-diphenylethanol(107059-12-1)
• EPA Substance Registry System: 2-ethoxy-1,2-diphenylethanol(107059-12-1)

Safety Data

• Hazardous Substances Data: 107059-12-1(Hazardous Substances Data)

Upstream product

• 51628-27-4 2,2-diethoxy-1,1-diphenylethan-1-ol 
• 574-09-4 2-ethoxy-1,2-diphenyl-ethanone 
• 100-52-7 benzaldehyde 
• 143064-49-7 1-(Ethoxy-phenyl-methyl)-1H-benzotriazole 
• 64-17-5 ethanol 
• 1689-71-0 cis-1,2-diphenyloxirane 

Downstream Products

• 574-09-4 2-ethoxy-1,2-diphenyl-ethanone 

Relevant articles and documents

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Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

We report an unprecedented organocatalytic enantioselective acyloin rearrangement of α,α-disubstituted α-hydroxy acetals. In the presence of a catalytic amount of chiral binol-derived N-triflyl phosphoramide, α-hydroxy acetals rearranged to α-alkoxy ketones in good to high yields with high enantioselectivities. Formation of an ion pair between the in situ generated oxocarbenium ion and the chiral phosphoramide anion was proposed to be responsible for the highly efficient transfer of chirality. Conditions for removal of cyclohexyl and cyclopentyl groups from the corresponding α-alkoxy ketones were uncovered underpinning their potential general utility as hydroxy protecting groups. Conversion of the rearranged products to the enantioenriched α-hydroxy ketone, 1,2-diol, β-amino alcohol and 1,4-dioxane was also documented.

Novel deoxygenation reaction of epoxides by indium

A novel, mild, ecofriendly protocol for the deoxygenation of epoxides to alkenes using indium metal and indium(I) chloride or ammonium chloride in alcohol has been developed. It was necessary for the presence of good radical-stabilizing groups adjacent to the oxirane ring for the deoxygenation reaction to occur. It is proposed that this reaction occurs through an SET process with indium as an electron donor.