107089-77-0

Basic information

• Product Name: 3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide
• Synonyms: 3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide;3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-
• CAS NO: 107089-77-0
• Molecular Formula: C₉H₉ClN₂O₂S
• Molecular Weight: 244.69796
• Mol File: 107089-77-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 395.9°Cat760mmHg
• Flash Point: 193.2°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 1.78E-06mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide(107089-77-0)
• EPA Substance Registry System: 3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide(107089-77-0)

Safety Data

• Hazardous Substances Data: 107089-77-0(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-ethyl-4H-1,2,4-benzothiadiazin-1,1-dioxide, also known as acetazolamide, is a chemical compound with the molecular formula C4H6ClN3O2S. It is a white crystalline powder with a bitter taste and is primarily used as a diuretic or to treat glaucoma. Acetazolamide works by decreasing the production of fluid in the eye, which helps to lower the intraocular pressure. It is also used to prevent and treat symptoms of acute mountain sickness, as it helps to decrease the buildup of bodily fluids, thereby reducing symptoms such as headache, tiredness, and shortness of breath at high altitudes. Additionally, acetazolamide is used in the treatment of certain kidney disorders and for the prevention of seizures in certain conditions. However,

InChI:InChI=1/C9H9ClN2O2S/c1-2-12-7-5-3-4-6-8(7)15(13,14)11-9(12)10/h3-6H,2H2,1H3

Upstream product

• 102308-74-7 4-ethyl-2H-1,2,4-benzothiadiazine-3 (4H)-one 1,1-dioxide 
• 103-69-5 N-ethyl-N-phenylamine 
• 147192-77-6 N-[3-[3-(piperidinomethyl)phenoxy]propyl]-4'-methoxybenzylamine 

Downstream Products

• 107089-80-5 3-hydrazino-4-ethyl-4H-1,2,4-benzothiadiazine 1,1-dioxide 
• 107089-83-8 3-(3,5-Dimethyl-pyrazol-1-yl)-4-ethyl-4H-benzo[1,2,4]thiadiazine 1,1-dioxide 
• 107089-86-1 2-(4-Ethyl-1,1-dioxo-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-5-methyl-2,4-dihydro-pyrazol-3-one 
• 1280555-57-8 C₂₃H₂₇FN₆O₄S 
• 1280555-64-7 C₃₆H₃₄ClFN₆O₆S 
• 1280555-27-2 C₂₃H₂₆FN₅O₅S 
• 1280555-33-0 C₂₃H₂₆FN₅O₄S₂ 
• 1280555-46-5 (S)-[{N-3-[3-fluoro-4-(4-(4-ethyl-1,1-dioxo-1,4-dihydro-1,2,4-benzothiadiazin-3-yl)piperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]acetamide 
• 1280555-51-2 (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-ethyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione 

Relevant articles and documents

Anti-tubercular agents. Part 3. Benzothiadiazine as a novel scaffold for anti-Mycobacterium activity

In an effort to develop new and more effective therapies to treat tuberculosis, a series of benzothiadiazine 1,1-dioxide derivatives were synthesized and their in vitro activity against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium int

Synthesis and biological evaluation of 6-alkyl/aryl quinazolino-[3,2-b][1,2,4]benzothiadiazine-13(6H)-one 11,11-dioxides

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