1071017-64-5

Basic information

• Product Name: N-tert-butyl-3-methylisonicotinamide
• CAS NO: 1071017-64-5
• Molecular Weight: 192.261
• Mol File: 1071017-64-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-tert-butyl-3-methylisonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyl-3-methylisonicotinamide(1071017-64-5)
• EPA Substance Registry System: N-tert-butyl-3-methylisonicotinamide(1071017-64-5)

Safety Data

• Hazardous Substances Data: 1071017-64-5(Hazardous Substances Data)

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 1003-73-2 3-picoline-N-oxide 
• 7584-05-6 3-methyl-4-cyanopyridine 
• 540-88-5 acetic acid tert-butyl ester 
• 65321-30-4 N-(tert-Butyl)pyridine-4-carboxamide 
• 74-88-4 methyl iodide 
• 4021-12-9 3-methyl-isonicotinic acid 
• 75-64-9 tert-butylamine 

Downstream Products

• 1071137-22-8 [4-(1-chloro[2,6]naphthyridin-3-yl)pyridin-2-yl]cyclohexylamine 
• 1071137-19-3 3-(2-cyclohexylaminopyridin-4-yl)-[2,6]naphthyridin-1-ol 
• 1071137-15-9 cyclohexyl-[4-(1-methoxy-[2,6]naphthyridin-3-yl)pyridin-2-yl]amine 
• 1071137-73-9 [3-chloro-4-(1-chloro-[2,6]naphthyridin-3-yl)pyridin-2-yl]cyclohexylamine 
• 1071137-70-6 [5-chloro-4-(1-chloro-[2,6]naphthyridin-3-yl)pyridin-2-yl]cyclohexylamine 
• 1071137-66-0 [5-bromo-4-(1-chloro-[2,6]naphthyridin-3-yl)pyridin-2-yl]cyclohexylamine 
• 1071137-68-2 cyclohexyl-[3,5-dibromo-4-(1-chloro-[2,6]naphthyridin-3-yl)pyridin-2-yl]amine 
• 1071129-72-0 cyclohexyl-{4-[1-(4-methylpiperazin-1-yl)[2,6]naphthyridin-3-yl]pyridin-2-yl}amine 
• 1071137-53-5 4-[3-(2-chloropyridin-4-yl)-4-phenyl-[2,6]naphthyridin-1-yl]piperazine-1-carboxylic acid tert-butyl ester 
• 1071137-64-8 1-[3-(2-chloropyridin-4-yl)-4-(4-fluorophenyl)-[2,6]naphthyridin-1-yl]piperidine-4-carboxylic acid isobutylamide 
• 1071136-35-0 1-[3-(2-cyclohexylaminopyridin-4-yl)-4-methyl-[2,6]naphthyridin-1-yl]piperidine-4-carboxylic acid isobutylamide 
• 1071017-49-6 1-chloro-3-pyridin-4-yl[2,6]naphthyridine 

Relevant articles and documents

6-6 FUSED BICYCLIC HETEROARYL COMPOUNDS AND THEIR USE AS LATS INHIBITORS

The present invention is related to 6-6 Fused Bicyclic Heteroaryl Compounds of the Formula A2 or A1 and their Use as LATS Inhibitors, or a salt, stereoisomer or pharmaceutical composition thereof; wherein the variables are as defined herein (A1 and A2). The present invention further relates to a method of LATS inhibition in a cell population using a compound of Formula A1, or a salt, stereoisomer or pharmaceutical composition thereof. The present invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, their use in the treatment and management of diseases or disorders.

[2, 6] NAPHTHYRIDINES USEFUL AS PROTEIN KINASE INHIBITORS

The present invention provides a compound of formula I: (formula I) said compound is inhibitor of selective subset of kinases belonging to the AGC or calmodulin kinase family, such as for example MARK1/2/3, PKD-1/2/3, PKN-1/2, CDK-9, CaMKII, ROCK-I/II, inhibitors of histone deacetylase (HDAC) phosphorylation, or inhibitors of other kinases. Finally, the present invention also provides a pharmaceutical composition.