1071789-01-9

Basic information

• Product Name: 5-((4-octyl-1H-1,2,3-triazol-1-yl)methyl)-3-phenyloxazolidin-2-one
• CAS NO: 1071789-01-9
• Molecular Weight: 356.468
• Mol File: 1071789-01-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-((4-octyl-1H-1,2,3-triazol-1-yl)methyl)-3-phenyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-((4-octyl-1H-1,2,3-triazol-1-yl)methyl)-3-phenyloxazolidin-2-one(1071789-01-9)
• EPA Substance Registry System: 5-((4-octyl-1H-1,2,3-triazol-1-yl)methyl)-3-phenyloxazolidin-2-one(1071789-01-9)

Safety Data

• Hazardous Substances Data: 1071789-01-9(Hazardous Substances Data)

Upstream product

• 764-93-2 1-decyne 
• 367925-74-4 5-azidomethyl-3-phenyl-1,3-oxazolidin-2-one 

Relevant articles and documents

Synthesis of triazole-oxazolidinones via a one-pot reaction and evaluation of their antimicrobial activity

C-5-substituted triazole-oxazolidinones were synthesized using a bromide catalyzed cycloaddition between aryl isocyanates and epibromohydrin followed by a three-component Huisgen cycloaddition. The library of compounds was screened for antibacterial activity against Mycobacterium smegmatis ATCC 14468, Bacillus subtilis ATCC 6633, and Enterococcus faecalis ATCC 29212. Notably, the 3-(4-acetyl-phenyl)-5-(1H-1,2,3-triazol-1-yl)methyl)-oxazolidin-2-one (18) showed an MIC of 1 μg/mL against M. smegmatis ATCC 14468, fourfold lower than the MIC measured for isoniazid.