107196-98-5Relevant articles and documents
New antiprotozoal agents: Synthesis and biological evaluation of different 4-(7-chloroquinolin-4-yl) piperazin-1-yl)pyrrolidin-2-yl)methanone derivatives
Ansari, Mohammad Fawad,Hayat, Faisal,Inam, Afreen,Kathrada, Fatima,van Zyl, Robyn L.,Coetzee, Maureen,Ahmad, Kamal,Shin, Dongyun,Azam, Amir
, p. 460 - 465 (2017)
In an endeavor to develop efficacious antiprotozoal agents 4-(7-chloroquinolin-4-yl) piperazin-1-yl)pyrrolidin-2-yl)methanone derivatives (5–14) were synthesized, characterized and biologically evaluated for antiprotozoal activity. The compounds were scre
PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL
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, (2008/06/13)
A 2- or 4-nitrobenzenesulfonamide is allowed to react with an alkali metal alkoxide to remove a nitrobenzenesulfonyl group to thereby obtain an amine corresponding to the amide. Furthermore, a method for producing an amine derivative by allowing the resulting amine without isolation to react with an activated, substituted oxycarbonyl compound or an activated acyl compound is provided. According to this method, a corresponding free amine and its substituted derivative can be produced easily and industrially advantageously from the 2- or 4-nitrobenzenesulfonamide without using a thiol compound.