1072270-36-0

Basic information

• Product Name: {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-(5-trifluoromethyl-pyridin-2-yl)-amine
• Synonyms: {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-(5-trifluoromethyl-pyridin-2-yl)-amine
• CAS NO: 1072270-36-0
• Molecular Weight: 608.644
• Mol File: 1072270-36-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-(5-trifluoromethyl-pyridin-2-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-(5-trifluoromethyl-pyridin-2-yl)-amine(1072270-36-0)
• EPA Substance Registry System: {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-(5-trifluoromethyl-pyridin-2-yl)-amine(1072270-36-0)

Safety Data

• Hazardous Substances Data: 1072270-36-0(Hazardous Substances Data)

Upstream product

• 1072269-73-8 {2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-carbamic acid tert-butyl ester 
• 1072269-71-6 {2-[4-(1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethyl}-carbamic acid tert-butyl ester 
• 1072269-67-0 [2-(4-chloro-6-morpholin-4-yl-pyrimidin-2-yl)-ethyl]-carbamic acid tert-butyl ester 
• 1072269-65-8 2-(4-chloro-6-morpholin-4-yl-pyrimidin-2-yl)-ethylamine 
• 1072269-75-0 2-[4-(1-benzenesulfonyl-1H-indol-4-yl)-6-morpholin-4-yl-pyrimidin-2-yl]-ethylamine 
• 69045-82-5 2-fluoro-5-(trifluoromethyl)pyridine 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS

The invention provides a compound which is a pyrimidine of formula (I): The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.