107259-69-8

Basic information

• Product Name: (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,2R)-2-isopropenyl-5,5-dimethyl-cyclohexyl ester
• CAS NO: 107259-69-8
• Molecular Weight: 384.439
• Mol File: 107259-69-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,2R)-2-isopropenyl-5,5-dimethyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,2R)-2-isopropenyl-5,5-dimethyl-cyclohexyl ester(107259-69-8)
• EPA Substance Registry System: (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1S,2R)-2-isopropenyl-5,5-dimethyl-cyclohexyl ester(107259-69-8)

Safety Data

• Hazardous Substances Data: 107259-69-8(Hazardous Substances Data)

Upstream product

• 5392-40-5 (E/Z)-3,7-dimethyl-2,6-octadienal 
• 17920-90-0 3,3,7-trimethyl-oct-6-enal 
• 104832-35-1 (1S,2R)-trans-5,5-dimethyl-2-(prop-1-en-2-yl)cyclohexanol 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 

Relevant articles and documents

ASYMMETRIC CYCLIZATION OF UNSATURATED ALDEHYDES CATALYZED BY A CHIRAL LEWIS ACID

A highly enantioselective cyclization of unsaturated aldehydes has been accomplished with the chiral zinc reagent 1 derived from dimethylzinc and (R)-(+)-1,1'-bi-2-naphthol.Thus, the Aldehyde 2 and 10 are treated with the reagent 1 producing the trans alcohol 3 and 11, respectively, with high optical purity (>90percent ee).In sharp contrast, the aldehyde 8 affords the totally racemic alcohol 9.Since the chiral zinc reagent 1 possesses its C2-symmetry, either enantiomer can be prepared from the unsaturated aldehyde by choosing the chiral ligand, (R)-(+)- or (S)-(-)-1,1'-bi-2-naphthol.