107267-01-6Relevant articles and documents
ZnO-mediated regioselective C-arylsulfonylation of indoles: A facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)
Tocco, Graziella,Begala, Michela,Esposito, Francesca,Caboni, Pierluigi,Cannas, Valeria,Tramontano, Enzo
, p. 6237 - 6241 (2013)
A ZnO-mediated one-pot solvent-free protocol for the regioselective C-arylsulfonylation of indoles is described and some novel derivatives were tested on wild type and non-nucleoside inhibitor resistant K103N and Y181C HIV-1 reverse transcriptases (RTs).
A simple and efficient approach for the sulfonylation of indoles catalyzed by CuI
Rahman, Matiur,Ghosh, Monoranjan,Hajra, Alakananda,Majee, Adinath
, p. 342 - 346 (2013/09/23)
In this paper, a simple and efficient protocol for the chemoselective sulfonation of indoles using aryl sulfonyl chlorides in the presence of CuI is reported. The reaction proceeds under mild conditions and is applicable to indoles bearing a selection of functional groups without NH protection.
Construction of Azacycles Based on Endo-Mode Cyclization of Allenes
Mukai, Chisato,Kobayashi, Minoru,Kubota, Shoko,Takahashi, Yukie,Kitagaki, Shinji
, p. 2128 - 2136 (2007/10/03)
A new procedure for constructing monocyclic five- and six-membered azacycles by the endo-mode ring-closing reaction of allenylazido derivatives under neutral conditions has been developed. The azabicyclo[m.n.0] compounds were prepared by applying this newly developed procedure. The seven-membered azacycle was prepared when the allene possessing an unsubstituted carboxyl amido functionality was submitted to the basic conditions. In addition, indole and quinoline skeletons were synthesized using this procedure.