107274-23-7Relevant articles and documents
Synthesis of phosphonomethoxyethyl or 1,3-bis(phosphonomethoxy)propan-2-yl lipophilic esters of acyclic nucleoside phosphonates
Vrbková, Silvie,Dra?ínsky, Martin,Holy, Antonín
, p. 11391 - 11398 (2007)
A new alternative synthetic pathway towards mono and diesters of acyclic nucleoside phosphonates (PMEA, PMEC and PMEG) or [1,3-bis(phosphonomethoxy)propan-2-yl]adenine bearing one or two hexadecyloxypropyl ester groups (CH2)3O-n-Csu
New technology for synthesizing 1,3-propylene glycol from glycerin through dehydroxylation method
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Paragraph 0021; 0022, (2017/05/12)
The invention discloses a new technology for synthesizing 1,3-propylene glycol from glycerin through a dehydroxylation method. The technology comprises the following steps: protecting two hydroxyl groups at the head end and the tail end of a glycerin molecule through using a group protection process, converting a hydroxyl group in the middle of the molecule into a group easy to eliminate, that is a sulfonyloxy group, removing hydroxyl group protection groups, and reducing the sulfonyloxy in the presence of a catalyst in order to obtain the 1,3-propylene glycol product. The technology has the characteristics of few byproducts, easiness in separation, and low cost, is a route with environmentally-friendly and economic dual values, and has wide development prospect.
Nitro-Imidazole Hypoxia Imaging Agents
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Page/Page column 13; 14, (2009/01/23)
The present invention relates to novel radioactively labeled bioreducible tracers of Formula I useful for detecting hypoxic tumors or ischemic tissue in vivo. In one embodiment, the tracers consist of a 2-nitroimidazole moiety, a triazole, metabolically s