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1072807-15-8

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1072807-15-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1072807-15-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,8,0 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1072807-15:
(9*1)+(8*0)+(7*7)+(6*2)+(5*8)+(4*0)+(3*7)+(2*1)+(1*5)=138
138 % 10 = 8
So 1072807-15-8 is a valid CAS Registry Number.

1072807-15-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name phenylbutyl isoselenocyanate

1.2 Other means of identification

Product number -
Other names ISC-4

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1072807-15-8 SDS

1072807-15-8Upstream product

1072807-15-8Downstream Products

1072807-15-8Relevant articles and documents

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates

Sharma, Arun K.,Sharma, Arati,Desai, Dhimant,Madhunapantula, SubbaRao V.,Sung, Jin Huh,Robertson, Gavin P.,Amin, Shantu

, p. 7820 - 7826 (2008)

Synthesis and identification of novel phenylalkyl isoselenocyanates (ISCs), isosteric selenium analogues of naturally occurring phenylalkyl isothiocyanates (ITCs), as effective cytotoxic and antitumor agents are described. The structure - activity relationship comparison of ISCs with ITCs and effect of the increasing alkyl chain length in inhibiting cancer cell growth were evaluated on melanoma, prostate, breast, glioblastoma, sarcoma, and colon cancer cell lines. IC50 values for ISC compounds were generally lower than their corresponding ITC analogues. Similarly, in UACC 903 human melanoma cells, the inhibition of cell proliferation and induction of apoptosis were more pronounced with ISCs compared to ITCs. Further, ISCs and ITCs effectively inhibited melanoma tumor growth in mice following intraperitoneal xenograft. A similar reduction in tumor size was observed at 3 times lower doses of ISCs compared to corresponding ITCs.

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