1073635-51-4

Basic information

• Product Name: 5-[1-(3-fluoro-5-trifluoromethyl-benzyl)-piperidin-4-ylamino]-[1,3,4]thiadiazole-2-carbonitrile
• Synonyms: 5-[1-(3-fluoro-5-trifluoromethyl-benzyl)-piperidin-4-ylamino]-[1,3,4]thiadiazole-2-carbonitrile
• CAS NO: 1073635-51-4
• Molecular Weight: 385.388
• Mol File: 1073635-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[1-(3-fluoro-5-trifluoromethyl-benzyl)-piperidin-4-ylamino]-[1,3,4]thiadiazole-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[1-(3-fluoro-5-trifluoromethyl-benzyl)-piperidin-4-ylamino]-[1,3,4]thiadiazole-2-carbonitrile(1073635-51-4)
• EPA Substance Registry System: 5-[1-(3-fluoro-5-trifluoromethyl-benzyl)-piperidin-4-ylamino]-[1,3,4]thiadiazole-2-carbonitrile(1073635-51-4)

Safety Data

• Hazardous Substances Data: 1073635-51-4(Hazardous Substances Data)

Upstream product

• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 
• 1073635-66-1 5-(piperidin-4-ylamino)-[1,3,4]thiadiazole-2-carbonitrile 
• 239087-09-3 1-(bromomethyl)-3-fluoro-5-(trifluoromethyl)benzene 

Relevant articles and documents

THIA(DIA)ZOLES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS

The present invention relates to [1- (benzyl) -piperidin-4-yl] -( [1, 3,4] thiadiazol-2-yl) - amine and [1- (benzyl) -piperidin-4-yl] - (thiazol-2-yl) -amine derivatives of formula (I) that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.