107399-99-5Relevant articles and documents
Synthesis of 2-(N-Substitutedarylcarbamoyl)-quinazolin-4(3H)-ones and Benzofurans as Potential Anthelmintics
Shukla, J. S.,Rastogi, Renu
, p. 774 - 775 (2007/10/02)
The 2-quinazolin-4(3H)-ones (7-17) and 2-benzofurans (20-30) have been synthesised and tested for their anthelmintic activity against Brugia pahangi and Hymenolepis nana in jirds and rats, respectively.Compound 29 is found to be the most active member of the series showing 65percent clearance of H. nana infection at a dose of 250 mg/kg for 3 days.