107544-71-8

Basic information

• Product Name: 1-benzyl-3-(naphthalen-1-yl)thiourea
• Synonyms: 1-benzyl-3-(naphthalen-1-yl)thiourea
• CAS NO: 107544-71-8
• Molecular Weight: 292.404
• Mol File: 107544-71-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-(naphthalen-1-yl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-(naphthalen-1-yl)thiourea(107544-71-8)
• EPA Substance Registry System: 1-benzyl-3-(naphthalen-1-yl)thiourea(107544-71-8)

Safety Data

• Hazardous Substances Data: 107544-71-8(Hazardous Substances Data)

Usage

Chemical structure

Thiourea derivative with a benzyl group attached to the nitrogen atom and a naphthalen-1-yl group attached to the thiourea sulfur atom.

Chelating agent

Capable of binding to metal ions.

Antitumor properties

Potentially effective against cancer cells.

Antiviral properties

Potentially effective against viral infections.

Organic semiconductors

Investigated for use in the development of organic semiconductors.

Versatility

Wide range of potential applications in various fields, including pharmaceuticals, materials science, and environmental science.

Upstream product

• 134-32-7 1-amino-naphthalene 
• 622-78-6 Benzyl isothiocyanate 
• 551-06-4 1-isothiocyanatonaphthalene 
• 100-46-9 benzylamine 
• 29647-76-5 (naphth-1-ylamino)phenoxymethane-1-thione 

Downstream Products

• 130412-95-2 Benzyl-naphthalen-1-yl-carbodiimide 
• 7669-07-0 (2-benzylimino-3-naphthalen-1-yl-4-oxo-thiazolidin-5-yl)-acetic acid 

Relevant articles and documents

Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines

A mild, broadly functional group tolerant methodology has been developed to access a variety of mono- and bis-carbodiimides in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguandines.

Convenient synthesis of unsymmetrical N,N′-disubstituted thioureas in water

A simple and convenient two-step method has been developed and used to synthesise 25 (4 of which are novel) unsymmetrical N,N′-disubstituted thioureas in water. Alkylamines or variously substituted arylamines reacted smoothly with phenyl chlorothionoformate at room temperature to form thiocarbamates, which were then reacted with another alkyl- or arylamine in water at reflux to afford the unsymmetrical N,N′-disubstituted thioureas in good to excellent yields. Mild conditions, simple work-up, high yields as well as using water as solvent are the major advantages of the method.