107646-64-0

Basic information

• Product Name: 2-chloro-3-phenoxypropanol
• Synonyms: 2-chloro-3-phenoxypropanol
• CAS NO: 107646-64-0
• Molecular Weight: 186.638
• Mol File: 107646-64-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-chloro-3-phenoxypropanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-phenoxypropanol(107646-64-0)
• EPA Substance Registry System: 2-chloro-3-phenoxypropanol(107646-64-0)

Safety Data

• Hazardous Substances Data: 107646-64-0(Hazardous Substances Data)

Upstream product

• 106-89-8 epichlorohydrin 
• 108-95-2 phenol 
• 122-60-1 Phenyl glycidyl ether 
• 1746-13-0 allyl phenyl ether 

Relevant articles and documents

Regioselective conversion of unsymmetrical terminal epoxides into vicinal chlorohydrins using dimethoxyboron chloride

A highly regioselective synthesis of chlorohydrins by chlorinative cleavage of unsymmetrical epoxides utilizing dimethoxyboron chloride is described. Except for styrene oxide, all the terminal epoxides were regioselectively cleaved following a predominantly SN2-type reaction pathway favouring the formation of primary chlorides. In the case of styrene oxide, a benzylic epoxide, (MeO)2BCl transfers the chlorine at the benzylic position, by following an apparent SN1-type mechanism. CSIRO 2006.

Convenient synthesis of chlorohydrins from epoxides using zinc oxide: Application to 5,6-epoxysitosterol

Efficient synthesis of protected and unprotected chlorohydrins has been achieved by ring opening of epoxides with acetyl/benzoyl chloride and TMSCl using a catalytic amount of ZnO as a reusable catalyst. The applicability of ZnO is further extended by performing the cleavage of the natural product 5,6-epoxysitosterol with acetyl chloride.