107679-25-4

Basic information

• Product Name: but-2-enedioic acid tert-butyl ester ethyl ester
• Synonyms: but-2-enedioic acid tert-butyl ester ethyl ester
• CAS NO: 107679-25-4
• Molecular Weight: 200.235
• Mol File: 107679-25-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: but-2-enedioic acid tert-butyl ester ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: but-2-enedioic acid tert-butyl ester ethyl ester(107679-25-4)
• EPA Substance Registry System: but-2-enedioic acid tert-butyl ester ethyl ester(107679-25-4)

Safety Data

• Hazardous Substances Data: 107679-25-4(Hazardous Substances Data)

Upstream product

• 2459-05-4 (E)-4-ethoxy-4-oxobut-2-enoic acid 
• 75-65-0 tert-butyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1663-39-4 tert-Butyl acrylate 
• 140-88-5 ethyl acrylate 
• 115-11-7 isobutene 

Downstream Products

• 2459-05-4 (E)-4-ethoxy-4-oxobut-2-enoic acid 
• 288855-47-0 (2RS,3RS)-N-{[3-tert-butoxycarbonyl aziridine-2-yl]carbonyl}-(S)-leucyl-(S)-proline benzyl ester 
• 405873-33-8 2-(hydroxy-phenyl-methyl)-3-phenylsulfanyl-succinic acid 4-tert-butyl ester 1-ethyl ester 

Relevant articles and documents

Reagent-Controlled α-Selective Dehydrative Glycosylation of 2,6-Dideoxy Sugars: Construction of the Arugomycin Tetrasaccharide

The first synthesis of the tetrasaccharide fragment of the anthracycline natural product Arugomycin is described. A reagent controlled dehydrative glycosylation method involving cyclopropenium activation was utilized to synthesize the α-linkages with complete anomeric selectivity. The synthesis was completed in 20 total steps, and in 2.5% overall yield with a longest linear sequence of 15 steps.

Heterocyclic sodium/proton exchange inhibitors and method

Heterocyclic are provided which are sodium/proton exchange (NHE) inhibitors which have the structure wherein n is 1 to 5; X is N or C—R5 wherein R5 is H, halo, alkenyl, alkynyl, alkoxy, alkyl, aryl or heteroaryl; Z is a heteroaryl gorup, R1, R2, R3 and R4 are as defined herein, and where X is N. R1 is preferably aryl or heteroaryl, and are useful as antianginal and cardioprotective agents. In addition, a method is provided for preventing or treating angina pectoris, cardiac dysfunction, myocardial necrosis, and arrhythmia employing the above heterocyclic derivatives.

Tandem [4+2]/[3+2] cycloadditions of nitroalkenes. 9. Synthesis of (-)-rosmarinecine

(-)-Rosmarinecine (2) is the necine base portion of the pyrrolizidine alkaloid (-)-rosmarinine. (-)Rosmarinecine is a representative of the group of pyrrolizidines that show a cis relationship between adjacent stereocenters C(1), C(7), and C(7a), in addition to a highly oxygenated skeleton. (-)-Rosmarinecine (2) has been synthesized in eight steps and 14.8% overall yield, as an illustration of a general approach for the construction of pyrrolizidines having this stereochemical feature. The key step in the asymmetric synthesis is a Lewis acid-promoted, tandem inter-[4+2]/intra-[3+2] cycloaddition between a fumaroyloxy nitroalkene and a chiral vinyl ether.