107833-76-1Relevant articles and documents
Catalytic Asymmetric Synthesis of Isoxazolines from Silyl Nitronates
Han, Xiaoyu,Dong, Li,Geng, Caiwei,Jiao, Peng
supporting information, p. 3194 - 3197 (2015/07/15)
1,3-Dipolar cycloadditions of triisopropylsilyl nitronates and 2-alkylacroleins produced isoxazolines bearing a chiral quaternary center in high yields and enantioselectivities with the aid of a chiral oxazaborolidine catalyst. One chiral isoxazoline product was converted to (R)-(+)-Tanikolide in 9 steps in a total yield of 43%. (Chemical Equation Presented).
3-Nitropropanal and 3-Nitropropanol: Preparation of the Parent Compounds and Derivatives
Oehrlein, Reinhold,Schwab, Wilfried,Ehrler, Rudolf,Jaeger, Volker
, p. 535 - 538 (2007/10/02)
3-Nitropropanal has been prepared for the first time by 1,4-nitrite addition to acrolein.Several acetals of 3-nitropropanal are described, as well as 3-nitropropanol and some of its ethers. 3-Nitropropanol has been obtained by borane-dimethyl sulfide reduction of both 3-nitropropanal and 3-nitropropanoic acid.These reactions make available a variety of nitro compounds known as, or expected to become, highly useful and versatile building blocks for organic syntheses.