107967-05-5Relevant articles and documents
Fluoride-catalyzed Michael addition of nitrotoluenes to activated α, β-unsaturated esters
Li, Wen-Sen,Thottathil, John,Murphy, Michael
, p. 6591 - 6594 (2007/10/02)
We have found that in the presence of fluoride ion, nitrotoluenes of type 1 undergo Michael addition to activated α, β-unsaturated esters of type 2 in good to excellent yield (Scheme 1). The generality and limitation of this reaction and its application t
Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site
Kimball,Floyd,Das,Hunt,Krapcho,Rovnyak,Duff,Lee,Moquin,Turk,Hedberg,Moreland,Brittain,McMullen,Normandin,Cucinotta
, p. 780 - 793 (2007/10/02)
We have synthesized a series of benzazepinones (2) in order to determine the structure-activity relationships (SAR) for calcium channel blockers related to diltiazem. A prerequisite for calcium channel blocking activity in vitro and in vivo is the presenc
Benzazepine derivatives
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, (2008/06/13)
Vasodilating activity is exhibited by compounds having the formula STR1 and pharmaceutically acceptable salts thereof.