108-09-8 Usage
Description
1,3-Dimethylbutylamine is a clear, colorless liquid with a distinct fishlike odor. It is less dense than water and has a flash point ranging from 39 to 55°F. The vapors of this compound are heavier than air, and it may be toxic if ingested, inhaled, or absorbed through the skin.
Uses
1. Used in Chromatography Applications:
1,3-Dimethylbutylamine is used as a study agent for the application of unfunctionized polymethacrylate resin (TSKgel G3000PWXL) as a stationary phase in liquid chromatography with UV detection. This application helps in understanding the behavior and separation capabilities of the resin in various chromatographic processes.
2. Used in Chemical Synthesis:
1,3-Dimethylbutylamine can be used as a reagent or intermediate in the synthesis of various organic compounds, taking advantage of its amine functional group and unique structural properties.
3. Used in Pharmaceutical Industry:
Due to its amine nature, 1,3-Dimethylbutylamine may be utilized in the development of pharmaceutical compounds, potentially serving as a building block for the creation of new drugs or drug candidates.
4. Used in Research and Development:
The compound can be employed in research and development settings to study its properties, reactivity, and potential applications in various chemical and biological processes.
5. Used in Analytical Chemistry:
1,3-Dimethylbutylamine may be used as a reference compound or standard in analytical chemistry for the calibration of instruments and the development of new analytical methods.
Please note that the specific applications mentioned above are inferred from the general properties and characteristics of 1,3-Dimethylbutylamine. The actual uses may vary depending on the industry and specific requirements.
Air & Water Reactions
Highly flammable. Slightly soluble in water. May be air sensitive.
Reactivity Profile
1,3-Dimethylbutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Safety Profile
Poison by intravenous
route. Moderately toxic by ingestion and
skin contact. Mildly toxic by inhalation. A
dangerous fire and explosion hazard when
exposed to heat or flame; can react
vigorously with oxidizing materials. To fight
fire, use foam, CO2 dry chemical. When
heated to decomposition it emits toxic
fumes of NOx See also MINES.
Check Digit Verification of cas no
The CAS Registry Mumber 108-09-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 108-09:
(5*1)+(4*0)+(3*8)+(2*0)+(1*9)=38
38 % 10 = 8
So 108-09-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H15N/c1-5(2)4-6(3)7/h5-6H,4,7H2,1-3H3/p+1/t6-/m1/s1
108-09-8Relevant articles and documents
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Kuffner,F. et al.
, p. 469 - 475 (1962)
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Norton et al.
, p. 1054,1055 (1952)
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Karrer,Dinkel
, p. 122,126 (1953)
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Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds
Xie, Chao,Song, Jinliang,Hua, Manli,Hu, Yue,Huang, Xin,Wu, Haoran,Yang, Guanying,Han, Buxing
, p. 7763 - 7772 (2020/08/21)
Efficient synthesis of primary amines via low-temperature reductive amination of carbonyl compounds using NH3 and H2 as the nitrogen and hydrogen resources is highly desired and challenging in the chemistry community. Herein, we employed naturally occurring phytic acid as a renewable precursor to fabricate titanium phosphate (TiP)-supported Ru nanocatalysts with different reduction degrees of RuO2 (Ru/TiP-x, x represents the reduction temperature) by combining ball milling and molten-salt processes. Very interestingly, the obtained Ru/TiP-100 had good catalytic performance for the reductive amination of carbonyl compounds at ambient temperature, resulting from the synergistic cooperation of the support (TiP) and the Ru/RuO2 with a suitable proportion of Ru0 (52%). Various carbonyl compounds could be efficiently converted into the corresponding primary amines with high yields. More importantly, the conversion of other substrates with reducible groups could also be achieved at ambient temperature. Detailed investigations indicated that the partially reduced Ru and the support (TiP) were indispensable. The high activity and selectivity of Ru/TiP-100 catalyst originates from the relatively high acidity and the suitable electron density of metallic Ru0.
Rapid synthesis method of biomass-based amide
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Paragraph 0058; 0061-0063, (2019/01/15)
The invention discloses a rapid synthesis method of biomass-based amide, which comprises the steps: formamide is used as an amine source, formic acid is used as a hydrogen source, biomass aldehyde andketone is used as a raw material, the direct addition of formamide and aldehyde and ketone components and the reduction of formic acid is promoted to prepare the corresponding formamide derivative byrapidly heating under microwave-assisted heating and in the absence of a solvent and a catalyst; the formamide derivative is selectively converted to the corresponding primary amide by alcoholysis under the action of a base. The microwave assisted heating reaction system of the invention has higher catalytic efficiency than the corresponding oil bath system, greatly shortens the reaction time, remarkably improves the selectivity. The conversion rate of the biomass aldehyde or ketone compound is at least 99%, and the yield of the formamide derivative can reach 85 to 99%; the formamide can be synthesized by alcoholysis to obtain a primary amide with a yield of 92 to 99%.