108010-64-6

Basic information

• Product Name: 2-Propenoic acid, 3-[2-(pentyloxy)phenyl]-
• CAS NO: 108010-64-6
• Molecular Formula: C14H18O3
• Molecular Weight: 234.295
• Mol File: 108010-64-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-[2-(pentyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-[2-(pentyloxy)phenyl]-(108010-64-6)
• EPA Substance Registry System: 2-Propenoic acid, 3-[2-(pentyloxy)phenyl]-(108010-64-6)

Safety Data

• Hazardous Substances Data: 108010-64-6(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 110-53-2 1-Bromopentane 
• 6236-69-7 methyl 2-hydroxycinnamate 
• 543-59-9 1-Chloropentane 
• 7091-14-7 2-pentyloxybenzaldehyde 
• 108-24-7 acetic anhydride 

Relevant articles and documents

New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships

(p-Amylcinnamoyl)anthranilic acid (3a) had moderate antagonist activities against LTD4-induced smooth muscle contraction on guinea pig ileum and LTC4-induced bronchoconstriction in anesthetized guinea pigs. Modifications were made in the hydrophobic part (cinnamoyl moiety) and the hydrophilic part (anthranilate moiety) of 3a. A series of 8-(benzoylamino)-2-tetrazol-5-yl-1,4-benzodioxans and 8-(benzoylamino)-2-tetrazol-5-yl-4-oxo-4H-1-benzopyrans were revealed to be potent antagonists of leukotrienes C4 and D4. Among both series, ONO-RS-347 (18k) and ONO-RS411 (19h) were the most potent and orally active antagonists, respectively. Structure-activity relationships are discussed.