108056-65-1

Basic information

• Product Name: methyl (S)-(-)-5-oxo-3-phenylhexanoate
• Synonyms: methyl (S)-(-)-5-oxo-3-phenylhexanoate
• CAS NO: 108056-65-1
• Molecular Weight: 220.268
• Mol File: 108056-65-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: methyl (S)-(-)-5-oxo-3-phenylhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-(-)-5-oxo-3-phenylhexanoate(108056-65-1)
• EPA Substance Registry System: methyl (S)-(-)-5-oxo-3-phenylhexanoate(108056-65-1)

Safety Data

• Hazardous Substances Data: 108056-65-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 108056-64-0 (S)-5-oxo-3-phenylhexanoic acid 
• 67-56-1 methanol 
• 1896-62-4 (E)-benzalacetone 
• 131177-38-3 (S)-3-(4-Chloro-phenyl)-5-oxo-hexanoic acid methyl ester 
• 108341-92-0 (Z)-3-((S)-1-tert-Butoxycarbonyl-2-methyl-propylamino)-but-2-enoic acid ethyl ester 
• 5292-53-5 diethyl benzalmalonate 
• 32046-34-7 di-tert-butyl 2-benzylidenemalonate 
• 6626-84-2 dimethyl 2-benzylidenepropanedioate 
• 1352755-81-7 (S)-5-acetyl-6-methyl-4-phenyl-3,4-dihydro-2H-pyran-2-one 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1331750-78-7 (S)-ethyl 6-methyl-2-oxo-4-phenyl-3,4-dihydro-2H-pyran-5-carboxylate 
• 14371-10-9 (E)-3-phenylpropenal 
• 130143-05-4 (7S,10R)-3-(4-Chloro-benzylidene)-7-isopropyl-10-methyl-1,5-dioxa-spiro[5.5]undecane-2,4-dione 

Downstream Products

• 131906-00-8 (3S)-p-nitrophenyl 5-oxo-3-phenylhexanoate 
• 132046-18-5 (S)-p-nitrophenyl 5-methyl-3-phenylhex-5-enoate 
• 132046-17-4 (R)-p-nitrophenyl 5-methyl-3-phenylhex-5-enoate 
• 122020-05-7 (3S)-N-((1R)-1-phenyl-2-hydroxyethyl)-5-oxo-3-phenylhexanamide 
• 122020-04-6 (3R)-N-((1R)-1-phenyl-2-hydroxyethyl)-5-oxo-3-phenylhexanamide 
• 108056-64-0 (S)-5-oxo-3-phenylhexanoic acid 

Relevant articles and documents

Asymmetric synthesis of δ-keto esters via Michael additions of chiral carbene complexes

The asymmetric Michael addition of the enolates of chiral imidazolidinone carbene complexes to α,β-unsaturated ketones occur with high induction.

DBU-Catalyzed Ring-Opening and Retro-Claisen Fragmentation of Dihydropyranones

We present a general protocol for the formal Michael addition of acetone to α,β-unsaturated esters and amides, a transformation difficult to perform using current methods. The protocol comprises of an amidine catalyzed relay ring-opening and fragmentation

A general organocatalytic enantioselective malonate addition to α,β-unsaturated enones

A general enantioselective organocatalytic conjugate addition procedure of a variety of malonates to α,β-unsaturated enone systems is presented. The reaction is efficiently catalysed by the pyrrolidinyl tetrazole catalyst 1. Cyclic, acyclic and aromatic e

Asymmetric Mukaiyama-Michael Addition of Acyclic Enones Catalyzed by allo-Threonine-Derived B-Aryloxazaborolidinones

(Formula Presented) O-(2-Naphthoyl)-N-tosyl-L-allo-threonine-derived B-phenyloxazaborolidinone catalyzes the asymmetric Mukaiyama-Michael addition of simple acyclic enones to give adducts of 54-85% ee. 2,6-Diisopropylphenol as an additive is demonstrated