108183-41-1

Basic information

• Product Name: tetraethyl (N-benzoylaminomethyl)bisphosphonate
• Synonyms: tetraethyl (N-benzoylaminomethyl)bisphosphonate
• CAS NO: 108183-41-1
• Molecular Weight: 407.34
• Mol File: 108183-41-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tetraethyl (N-benzoylaminomethyl)bisphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: tetraethyl (N-benzoylaminomethyl)bisphosphonate(108183-41-1)
• EPA Substance Registry System: tetraethyl (N-benzoylaminomethyl)bisphosphonate(108183-41-1)

Safety Data

• Hazardous Substances Data: 108183-41-1(Hazardous Substances Data)

Upstream product

• 108183-32-0 diethyl α-bromo-α-(benzoylamino)methylphosphonate 
• 122-52-1 triethyl phosphite 
• 20495-33-4 diethyl N-benzoyl-α-aminomethylphosphonate 
• 122-51-0 orthoformic acid triethyl ester 
• 98-88-4 benzoyl chloride 

Downstream Products

• 78980-62-8 diethyl [1-(benzoylamino)ethen-1-yl]phosphonate 

Relevant articles and documents

1-Aminovinylphosphonate Esters as Substrates for the Diels-Alder Reaction: First Synthetic and Theoretical Study

The Diels-Alder reaction of 1-aminovinylphosphonate esters has been studied for the first time as a suitable procedure leading to quaternary carbocyclic α-aminophosphonates. The reaction is influenced by steric effects at the phosphonate functionality (bulky groups hinder the reaction) and electronic effects at the amino group (electron-withdrawing substituents increase the reaction rate). The exo/endo ratio is constant, and no influence of the solvent is observed. The experimental results have been rationalized by DFT methods.

Synthese von 1-Aminophosphonsaeure ueber Acyliminophosphonsaeure-Ester

1-Acylaminomethylphosphonates 1 on reaction with N-bromosuccinimide yield 1-acylamino-1-bromomethylphosphonates 2, which on treatment with tertiary amines are converted into acyliminophosphonates 3.The latter react in situ with nucleophiles like enamines,