108202-36-4Relevant articles and documents
Regioselective Construction of Functionalized Biarylols by Fe(OTf)3-Catalyzed Direct Arylation of 1-Diazonaphthalen-2(1H)-ones and Their Fluorescence Properties
Somai Magar, Krishna Bahadur,Edison,Lee, Yong Rok
, p. 7046 - 7054 (2017)
A facile and efficient protocol for the construction of functionalized biarylols by Fe(OTf)3-catalyzed direct arylation of 1-diazonaphthalen-2(1H)-ones with arenes has been developed. This methodology provides diverse 1-arylnaphthalen-2-ols in moderate to good yields. This approach has also been applied to the synthesis of biologically interesting polycyclic-aromatic-substituted and heteroaryl-substituted naphthalen-2-ols. The synthesized compounds bearing an anthracene scaffold can be useful as potential fluorescent biomarkers for confocal imaging of clone cells.
Carbon-Oxygen Homocoupling of 2-Naphthols through Electrochemical Oxidative Dearomatization
Chen, Ting,Chen, Song,Fu, Shaomin,Qin, Song,Liu, Bo
supporting information, p. 903 - 909 (2019/05/10)
A homocoupling reaction of 2-naphthols with formation of a C-O bond through electrochemical oxidative dearomatization in the presence of catalytic amounts of ferrocene and a ruthenium complex was developed. Mechanistic studies revealed that the reaction might proceed through coupling between two identical radical species. Moreover, a gram-scale experiment was performed to illustrate the potential practicability of this methodology in organic synthesis.
RuII-catalyzed vinylative dearomatization of naphthols via a C(sp2)-H bond activation approach
Nan, Jiang,Zuo, Zhijun,Luo, Lei,Bai, Lu,Zheng, Huayu,Yuan, Yini,Liu, Jingjing,Luan, Xinjun,Wang, Yaoyu
supporting information, p. 17306 - 17309 (2014/01/06)
Intermolecular annulation reactions of 1-aryl-2-naphthols with internal alkynes proceed efficiently in the presence of a Ru catalyst and a Cu oxidant to generate spirocyclic compounds by sequential cleavage of the C(sp 2)-H bond, migratory insertion of the alkyne, and dearomatization of the naphthyl ring. Various spirocyclic molecules bearing an all-carbon quaternary stereocenter could be obtained by this novel method with good yields and excellent regioselectivity, and the current process tolerates a variety of synthetically important functional groups.
