1082065-98-2

Basic information

• Product Name: 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde
• Synonyms: 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde
• CAS NO: 1082065-98-2
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.13992
• Mol File: 1082065-98-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 319.2±22.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.35±0.10(Predicted)
• CAS DataBase Reference: 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde(1082065-98-2)
• EPA Substance Registry System: 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde(1082065-98-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 1082065-98-2(Hazardous Substances Data)

Usage

Description

1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde is a chemical compound with the molecular formula C7H8N2O2. It is a derivative of pyrazole, which is a five-membered aromatic ring containing three carbon atoms and two nitrogen atoms. 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde contains a carbaldehyde group, which is a functional group consisting of a carbon atom bonded to both a hydrogen atom and an aldehyde group. The presence of a hydroxyethyl group indicates that there is a hydroxyl group attached to an ethyl group in the molecule. This chemical compound has potential applications in organic synthesis and medicinal chemistry due to its structural features.

Uses

Used in Organic Synthesis:
1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde is used as a building block for the synthesis of various organic compounds. Its unique structural features, including the carbaldehyde and hydroxyethyl groups, make it a versatile intermediate for the preparation of a wide range of chemical products.
Used in Medicinal Chemistry:
1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde is used as a key intermediate in the development of pharmaceuticals. Its structural features allow for the design and synthesis of novel drug candidates with potential therapeutic applications. 1-(2-hydroxyethyl)-1H-pyrazole-4-carbaldehyde's reactivity and functional groups can be exploited to create new molecules with desired biological activities and properties.

Upstream product

• 35344-95-7 1H-pyrazole-4-carbaldehyde 
• 540-51-2 2-bromoethanol 
• 68-12-2 N,N-dimethyl-formamide 
• 6314-23-4 1-(2-hydroxyethyl)-pyrazole 

Downstream Products

• 1082063-19-1 2-{4-[3'-(4-methoxymethyl-phenyl)-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-ylmethyl]-pyrazol-1-yl}-ethanol hydrochloride 

Relevant articles and documents

HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF

The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

The present invention relates to compounds acting both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists, to processes for their preparation, to compositions comprising them, to therapeutic uses and combinations with other pharmaceutical active ingredients.

2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.