108223-13-8

Basic information

• Product Name: 7-benzylidene-4-phenyl-3-cyano-2-thioxo-2,5,6,7-tetrahydro-1H-pyrindines
• Synonyms: 7-benzylidene-4-phenyl-3-cyano-2-thioxo-2,5,6,7-tetrahydro-1H-pyrindines
• CAS NO: 108223-13-8
• Molecular Weight: 340.448
• Mol File: 108223-13-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-benzylidene-4-phenyl-3-cyano-2-thioxo-2,5,6,7-tetrahydro-1H-pyrindines(CAS DataBase Reference)
• NIST Chemistry Reference: 7-benzylidene-4-phenyl-3-cyano-2-thioxo-2,5,6,7-tetrahydro-1H-pyrindines(108223-13-8)
• EPA Substance Registry System: 7-benzylidene-4-phenyl-3-cyano-2-thioxo-2,5,6,7-tetrahydro-1H-pyrindines(108223-13-8)

Safety Data

• Hazardous Substances Data: 108223-13-8(Hazardous Substances Data)

Upstream product

• 302554-25-2 2-(2-cyano-ethylsulfanyl)-4-phenyl-6,7-dihydro-5H-[1]pyrindine-3-carbonitrile 
• 68029-52-7 (E)-2-cyano-3-phenylprop-2-enethioamide 
• 120-92-3 cyclopentanone 
• 83236-48-0 4-phenyl-2-thioxo-2,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carbonitrile 
• 100-52-7 benzaldehyde 
• 7357-70-2 Cyanothioacetamide 
• 895-80-7 2,5-dibenzylidenecyclopentanone 
• 1921-90-0 2-benzylidenecyclopentanone 

Downstream Products

• 108223-20-7 1-(4-chlorophenyl)-3-(7-benzylidene-4-phenyl-5,6-dihydro-7H-thieno<2,3-b>pyrindin-3-yl)-urea 
• 108223-23-0 7-benzylidene-2-methyl-10-phenyl-8,9-dihydro-7H-pyrindino<2',3':2,3>thieno<4,5-d>-pyrimidin-4(3H)-one 
• 108223-22-9 7-benzylidene-2-methyl-10-phenyl-8,9-dihydro-7H-pyrindino<2',3':2,3>thieno<4,5-d><1,3>-oxazin-4-one 
• 108223-21-8 4-amino-7-benzylidene-10-phenyl-8,9-dihydro-7H-pyrindino<2',3':2,3>thieno<4,5-d>-pyrimidine 
• 108223-15-0 3-amino-7-benzylidene-2-carboxy-4-phenyl-5,6-dihydro-7H-thieno<2,3-b>pyrindine 
• 108223-19-4 3-amino-7-benzylidene-4-phenyl-5,6-dihydro-7H-thieno<2,3-b>pyrindine 
• 77821-81-9 7-Benzylidene-3-cyano-2-oxo-4-phenyl-2,5,6,7-tetrahydro-1H-1-pyrindine 
• 108255-37-4 C₂₄H₁₇N₃S 
• 108223-17-2 C₂₄H₁₉N₃OS 
• 108223-18-3 C₃₀H₂₂N₂OS 
• 108223-14-9 7-benzylidene-4-phenyl-3-cyano-5,6-dihydro-7H-2-pyrindinylthioacetic acid 
• 108223-16-1 C₂₆H₂₂N₂O₂S 

Relevant articles and documents

Synthesis, reactions and antimicrobial activity of new cyclopenta[e]thieno-[2,3-b]pyridines and related heterocyclic systems

Reaction of the arylidene cyanothioacetamides la, b with cyclopentanone was proved to give a mixture of 4-aryl-3-cyanocyclopenta[b]pyridine-2(1H)-thiones 2a, b and the corresponding 7-arylidene derivatives 3a, b. Compounds 2a, b were reacted with ethyl chloroacetate or chloroacetamide to give the promising S-substituted thiopyridines 6a-d. On treatment of the latter compounds with sodium ethoxide in boiling ethanol, they underwent intramolecular Thorpe-Ziegler cyclization to yield the corresponding 3-amino-4-aryl-2-functionalized-cyclopenta[e]thieno[2,3-b]pyridines (7a-d). Most of these thienopyridines were reacted with a variety of reagents to produce other new cyclopentathienopyridines as well as numerous of their condensed heterocyclic derivatives. Some of the compounds synthesized were tested in vitro for their antibacterial and antifungal activity.