1082747-30-5Relevant articles and documents
Catalytic amidation of 9-iodo-m-carborane and 2-iodo-p-carborane at a boron atom
Mukhin, Sergey N.,Kabytaev, Kuanysh Z.,Zhigareva, Galina G.,Glukhov, Ivan V.,Starikova, Zoya A.,Bregadze, Vladimir I.,Beletskaya, Irina P.
, p. 5937 - 5942 (2009/04/13)
The palladium-catalyzed amidation of B-iodocarboranes by various amides is described for the first time. The reactions of 2-iodo-1,12-dicarba-closo- dodecaborane (2-iodo-p-carborane) with acetamide, 2-pyrrolidinone, caprolactam, p-methylbenzamide, and 2-phenylacetamide using the system Pd(dba) 2/BINAP/NaH (dba = dibenzylideneacetone; BINAP = rac-2,2′- bis(diphenylphosphino)-1,1′-binaphthyl) in dioxane at 100°C gave 2-p-carboranyl derivatives of these amides in good to high yields. Similar reactions of 9-iodo-1,7-dicarba-closo-dodecaborane (9-iodo-m-carborane) with corresponding amides afforded 9-m-carboranyl derivatives in good to high yields. The structures of N-(1,12-dicarba-closo-dodecaboran-2-yl)pyrrolidin-2-one (5), N-(1,7-dicarba-closo-dodecaboran-9-yl)acetamide (6), and N-(1,7-dicarba-closo- dodecaboran-9-yl)-2-phenylacetamide (7) have been established by X-ray diffraction studies.
