1082747-84-9

Basic information

• Product Name: 2,2'-bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[5,5']biisoindolyl-1,3,1',3'-tetraone
• CAS NO: 1082747-84-9
• Molecular Weight: 787.012
• Mol File: 1082747-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2'-bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[5,5']biisoindolyl-1,3,1',3'-tetraone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[5,5']biisoindolyl-1,3,1',3'-tetraone(1082747-84-9)
• EPA Substance Registry System: 2,2'-bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[5,5']biisoindolyl-1,3,1',3'-tetraone(1082747-84-9)

Safety Data

• Hazardous Substances Data: 1082747-84-9(Hazardous Substances Data)

Upstream product

• 616885-86-0 N¹-ethyl-N¹-(2-methoxybenzyl)hexane-1,6-diamine 
• 2420-87-3 3,3',4,4'-biphenyltetracarboxylic anhydride 

Relevant articles and documents

Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer

Novel multi-target-directed ligands were designed by replacing the inner dipiperidino function of 3 with less flexible or completely rigid moieties to obtain compounds endowed with multiple biological properties that might be relevant to Alzheimer's disease. 15 was the most interesting, inhibiting AChE in the nanomolar range and inhibiting AChE-induced and self-promoted β-amyloid aggregation in the micromolar range.