108377-17-9Relevant articles and documents
Facile Conversion of Aldehydes into 1-Substituted 2-Chloro-3,3-difluoro-2-propen-1-ols with 1,1-Dibromo-1-chloro-2,2,2,-trifluoroethane/Magnesium Reagent
Fujita, Makoto,Hiyama, Tamejiro
, p. 3321 - 3322 (1988)
Aldehydes RCHO are converted in excellent yields into chlorodifluoroallyl alcohols RCH(OH)CCl=CF2 upon treatment with CClBr2CF3 and magnesium in tetrahydrofuran at 0 deg C.
Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and Zinc
Fujita, Makoto,Hiyama, Tamejiro
, p. 4377 - 4384 (2007/10/02)
Thermally stable zinc carbenoid CF3CCl2ZnCl was prepared from 1,1,1-trichloro-2,2,2-trifluoroethane and zinc powder in N,N-dimethylformamide and was allowed to add to carbonyls of aldehydes and α-keto esters in excellent yields to give 1-substituted 2,2-d