108434-79-3 Usage
Description
Acetic acid 8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-yl ester is a complex organic compound with a unique chemical structure. It is characterized by its ester functional group and a tetrahydroisoquinolin-4-yl moiety, which contributes to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
Acetic acid 8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-yl ester is used as an intermediate in the synthesis of Cotarnine Chloride (C717500), which is an oxidative degradation product of the drug Noscapine (N882000). Acetic acid 8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-yl ester plays a crucial role in the development of new pharmaceuticals, particularly those targeting various medical conditions.
Used in Chemical Synthesis:
Due to its unique chemical structure, Acetic acid 8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolin-4-yl ester can be utilized as a building block in the synthesis of other complex organic molecules. This makes it valuable in the field of organic chemistry and materials science, where it can contribute to the development of novel compounds with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 108434-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,3 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 108434-79:
(8*1)+(7*0)+(6*8)+(5*4)+(4*3)+(3*4)+(2*7)+(1*9)=123
123 % 10 = 3
So 108434-79-3 is a valid CAS Registry Number.
108434-79-3Relevant articles and documents
Practical Synthesis of 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxoloisoquinolin-5-ol (Cotarnine)
Shirasaka, Tadashi,Takuma, Yuki,Shimpuku, Tetsuro,Imaki, Naoshi
, p. 3767 - 3771 (2007/10/02)
5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxoloisoquinolin-5-ol (cotarnine, 1), an oxidative degradation product of (3S)-6,7-dimethoxy-3-isoquinolin-5-yl>phthalide (noscapine), has efficiently been synthesized from 2-methoxy-3,4-(methylenedioxy)benzaldehyde (7) in 66percent overall yield. -N-methylamino>acetaldehyde dimethyl acetal, obtained by reductive amination of 7 with aminoacetaldehyde dimethyl acetal followed by N-methylation, was cylized in acid to 5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxoloisoquinolin-8-ol (12).The major byproduct of the cyclization was C-8 methoxy derivative of 12, and the amount of this byproduct was decreased by removal of MeOH formed in the reaction mixture.Acetylation of the hydroxyl group in 12 and hydrogenolysis gave 5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxoloisoquinoline (hydrocotarnine), which was oxidized with I2 followed by basification to afford 1.