108463-45-2 Usage
Chemical class
Quinolinone derivatives
Physical appearance
Yellow to brown crystalline solid
Uses
Synthesis of pharmaceutical compounds, building block in organic chemistry, development of new materials and dyes
Specific properties
The specific properties of 2(1H)-Quinolinone,1,4,5,7-tetramethyl-(9CI) are not explicitly mentioned in the provided material. However, given its uses and chemical class, it is likely to have properties such as stability, reactivity, and solubility that make it useful in the mentioned applications.
Check Digit Verification of cas no
The CAS Registry Mumber 108463-45-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,6 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 108463-45:
(8*1)+(7*0)+(6*8)+(5*4)+(4*6)+(3*3)+(2*4)+(1*5)=122
122 % 10 = 2
So 108463-45-2 is a valid CAS Registry Number.
108463-45-2Relevant articles and documents
Ru-NHC-Catalyzed Asymmetric Hydrogenation of 2-Quinolones to Chiral 3,4-Dihydro-2-Quinolones
Daniliuc, Constantin,Glorius, Frank,Hu, Tianjiao,Lückemeier, Lukas
, p. 23193 - 23196 (2021/09/25)
Direct enantioselective hydrogenation of unsaturated compounds to generate chiral three-dimensional motifs is one of the most straightforward and important approaches in synthetic chemistry. We realized the Ru(II)-NHC-catalyzed asymmetric hydrogenation of 2-quinolones under mild reaction conditions. Alkyl-, aryl- and halogen-substituted optically active dihydro-2-quinolones were obtained in high yields with moderate to excellent enantioselectivities. The reaction provides an efficient and atom-economic pathway to construct simple chiral 3,4-dihydro-2-quinolones. The desired products could be further reduced to tetrahydroquinolines and octahydroquinolones.
