1085301-08-1Relevant articles and documents
A practical access to 1,2-diaminophytosphingolipids
Harrak, Youssef,Llebaria, Amadeu,Delgado, Antonio
experimental part, p. 4647 - 4654 (2009/05/07)
A practical approach to the synthesis of phytosphingolipids containing the 1,2-diamino framework is described. The methodology relies on the regioselective ring-opening of phytosphingosine-derived N-nosylaziridines 4 and 6 with primary or secondary amines, acylation and subsequent deprotection steps. For practical purposes, N-substituted benzylamines were used as protected primary amine surrogates to avoid side-reactions in the course of the N-nosyl deprotection step. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.