108579-13-1Relevant articles and documents
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. Trans-6-[2-(substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones
Prugh,Alberts,Deana,Gilfillian,Huff,Smith,Wiggins
, p. 758 - 765 (2007/10/02)
A variety of trans-6-[2-(substituted-1-naphthyl)ethyl(or ethyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones were prepared and, upon conversion to their 3,5-dihydroxy carboxylates, were found to have good inhibitory activity against the enzyme 3-hydroxy-