108606-59-3

Basic information

• Product Name: 2-[2-(4-Bromo-phenyl)hydrazono]cyclohexanone
• Synonyms: 2-[2-(4-Bromo-phenyl)hydrazono]cyclohexanone
• CAS NO: 108606-59-3
• Molecular Formula: C₁₂H₁₃BrN₂O
• Molecular Weight: 281.14842
• Mol File: 108606-59-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[2-(4-Bromo-phenyl)hydrazono]cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(4-Bromo-phenyl)hydrazono]cyclohexanone(108606-59-3)
• EPA Substance Registry System: 2-[2-(4-Bromo-phenyl)hydrazono]cyclohexanone(108606-59-3)

Safety Data

• Hazardous Substances Data: 108606-59-3(Hazardous Substances Data)

Upstream product

• 1193-63-1 Cyclohexanone-2-carbaldehyde 
• 39695-64-2 2-(hydroxymethylene)cyclohexanone 
• 106-40-1 4-bromo-aniline 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 765-87-7 cyclohexane-1,2-dione 
• 589-21-9 (4-bromophenyl)hydrazine 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 823-45-0 2-(hydroxymethylene)cyclohexanone 
• 108-94-1 cyclohexanone 

Downstream Products

• 59514-18-0 6-bromo-2,3,4,9-tetrahydro-1H-carbazol-1-one 

Relevant articles and documents

Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes

Aspects of the present disclosure include methods of reducing the deleterious impact of a target gene in a cell, such as the deleterious activity of a mutant extended nucleotide repeat (NR) containing target gene in a cell, by contacting the cell with an effective amount of an enantiomeric tetrahydrocarbazolamine compound. The deleterious activity (e.g., toxicity and/or dis-functionality of products encoded thereby) of a mutant extended NR containing target gene may be reduced, e.g., by reducing (and in some instances differentially, including selectively, reducing) the production or activity of toxic expression products (e.g., RNA or protein) encoded by the target gene. Kits and compositions for practicing the subject methods are also provided.

USE OF A DHODH INHIBITOR IN COMBINATION WITH AN INHIBITOR OF PYRIMIDINE SALVAGE

Compounds and methods are provided for the treatment of pathogenic virus infections or cancer. The formulations combine an inhibitor of de novo pyrimidine synthesis, and an inhibitor of a pyrimidine salvage pathway enzyme.

A novel CAN-SiO2-mediated one-pot oxidation of 1-keto-1,2,3,4-tetrahydrocarbazoles to carbazoloquinones: Efficient syntheses of murrayaquinone A and koeniginequinone A

One-pot oxidations of substituted 1-keto-1,2,3,4-tetrahydrocarbazoles (1) to carbazole-1,4-quinones (2) are efficiently carried out by CAN-SiO 2-mediated reaction. This generalized protocol was successfully extended to the synthesis of two naturally occurring carbazoloquinones: murrayaquinone A (2b) and koeniginequinone A (2g). A plausible mechanism for this novel reaction involves formation of a 9-hydroxy-2,3,4,9-tetrahydro-1H- carbazole-1-one followed by rearrangement to 1-hydroxycarbazole derivatives, which are further oxidized by cerium (IV) to carbazoloquinones.