1086391-03-8

Basic information

• Product Name: 3-chloro-1H-indazol-5-carbaldehyde
• Synonyms: 3-chloro-1H-indazol-5-carbaldehyde;3-Chloro-1H-indazole-5-carboxaldehyde;3-chloro-1H-indazole-5-carbaldehyde
• CAS NO: 1086391-03-8
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.5911
• Mol File: 1086391-03-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 190-195°C
• Appearance: /
• CAS DataBase Reference: 3-chloro-1H-indazol-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-1H-indazol-5-carbaldehyde(1086391-03-8)
• EPA Substance Registry System: 3-chloro-1H-indazol-5-carbaldehyde(1086391-03-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 2
• Hazardous Substances Data: 1086391-03-8(Hazardous Substances Data)

Usage

General Description

3-chloro-1H-indazol-5-carbaldehyde is a chemical compound with the molecular formula C9H6ClN3O. It is a derivative of indazole, which is a bicyclic aromatic heterocycle, and it contains a chloro and a formyl group. 3-chloro-1H-indazol-5-carbaldehyde is used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also known for its potential antimicrobial and antitumor properties. 3-chloro-1H-indazol-5-carbaldehyde has also been studied for its potential applications in materials science, particularly as a precursor for the synthesis of functional materials and dyes.

Upstream product

• 253801-04-6 1H-indazole-5-carbaldehyde 

Downstream Products

• 1450994-07-6 3-(4-(hydroxymethyl)phenyl)-1H-indazole-5-carbaldehyde 
• 1450994-05-4 3-(4-(methylthio)phenyl)-1H-indazole-5-carbaldehyde 

Relevant articles and documents

SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS

The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.