1086395-66-5 Usage
Description
2-methyl-2,7-diazaspiro[4.5]decane(SALTDATA: FREE) is a chemical compound characterized by its spirocyclic structure that features a diazaspiro group. It is widely recognized for its role as a building block in the synthesis of pharmaceuticals and agrochemicals, and it is also utilized as a chiral ligand in asymmetric catalysis and a precursor in the production of organic compounds.
Uses
Used in Pharmaceutical and Agrochemical Industries:
2-methyl-2,7-diazaspiro[4.5]decane(SALTDATA: FREE) is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and effective products in these fields.
Used in Asymmetric Catalysis:
In the field of catalysis, 2-methyl-2,7-diazaspiro[4.5]decane(SALTDATA: FREE) serves as a chiral ligand, playing a crucial role in asymmetric catalysis to produce enantiomerically pure compounds, which are essential in the synthesis of many pharmaceuticals and agrochemicals.
Used in Organic Compound Production:
2-methyl-2,7-diazaspiro[4.5]decane(SALTDATA: FREE) is also used as a precursor in the production of organic compounds, further expanding its utility in the realm of organic chemistry.
Used in Heterocyclic Compound Preparation:
2-methyl-2,7-diazaspiro[4.5]decane(SALTDATA: FREE) is employed in the preparation of heterocyclic compounds, which are important in various chemical and pharmaceutical applications.
Used in Drug Development:
Additionally, it is utilized in the development of potential drug candidates, showcasing its versatility and importance in the field of drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 1086395-66-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,6,3,9 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1086395-66:
(9*1)+(8*0)+(7*8)+(6*6)+(5*3)+(4*9)+(3*5)+(2*6)+(1*6)=185
185 % 10 = 5
So 1086395-66-5 is a valid CAS Registry Number.
1086395-66-5Relevant articles and documents
Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds
Weinberg, Kamil,Stoit, Axel,Kruse, Chris G.,Haddow, Mairi F.,Gallagher, Timothy
, p. 4694 - 4707 (2013/07/04)
The synthesis and differential substitution/protection of a series of spirodiamine scaffolds are described. Methods for selective access to the two mono-N-methyl isomers based on 2,7-diazaspiro[4.5]decane are also described. Key precursors associated with this chemistry are prone to rearrangement and methods for circumventing this issue are reported. While direct mono-carbamoylation (Boc) was not efficient, selective deprotection of doubly Boc-protected derivatives derived from symmetrical diamines provided mono-Boc variants. N-Arylation, exemplified by a series of monosubstituted spirodiamines incorporating the 2-chloro-5-pyridyl moiety, which is a privileged nicotinic agonist substructure, has also been carried out to provide monoarylated secondary and tertiary spirodiamines variants.
