108645-62-1

Basic information

• Product Name: 1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE
• Synonyms: LABOTEST-BB LT00453234;1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE;PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 2-METHYL ESTER;1,2-Pyrrolidinedicarboxylic acid, 2-Methyl 1-(phenylMethyl) ester
• CAS NO: 108645-62-1
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.29
• Mol File: 108645-62-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 375.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.220±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -3.40±0.40(Predicted)
• CAS DataBase Reference: 1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE(108645-62-1)
• EPA Substance Registry System: 1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE(108645-62-1)

Safety Data

• Hazardous Substances Data: 108645-62-1(Hazardous Substances Data)

Usage

General Description

1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate is a chemical compound with potential applications in the pharmaceutical industry. It is a derivative of pyrrolidone and is known for its psychoactive and stimulant properties. 1-BENZYL 2-METHYL PYRROLIDINE-1,2-DICARBOXYLATE has attracted interest in the scientific community for its potential as a cognitive enhancer and for its ability to improve memory and focus. It is also being investigated for its potential use in the treatment of certain neurological disorders. However, 1-benzyl 2-methyl pyrrolidine-1,2-dicarboxylate is also considered to be a controlled substance due to its psychoactive effects, and its use and distribution are regulated in many parts of the world.

Upstream product

• 124-41-4 sodium methylate 
• 144630-13-7 S-(3-mercaptopropyl) N-benzyloxycarbonylpyrrolidine-2-carbothioate 
• 67-56-1 methanol 
• 1148-11-4 N-carbobenzyloxyproline 
• 74-88-4 methyl iodide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 501-53-1 benzyl chloroformate 
• 609-36-9 rac-Pro-OH 
• 5454-83-1 5-bromovaleric acid methyl ester 
• 127811-93-2 5-azidovaleric acid methyl ester 
• 127811-84-1 2-(4-azidobut-1-ylidene)-1,3-dithiane 
• 127811-86-3 2--1,3-dithiane 
• 147-85-3 L-proline 
• 100-39-0 benzyl bromide 

Downstream Products

• 145681-01-2 (+/-)-N-tert-butoxycarbonylproline methyl ester 
• 127811-86-3 2--1,3-dithiane 
• 144630-13-7 S-(3-mercaptopropyl) N-benzyloxycarbonylpyrrolidine-2-carbothioate 
• 141870-95-3 (+/-)-1-benzyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate 
• 93271-97-7 1-benzyloxycarbonyl-5-hydroxy-2-methoxycarbonylpyrrolidine 
• 161417-43-2 1-Benzyloxycarbonyl-2-(methoxycarbonyl)-2-(2-propenyl)pyrrolidine 
• 213014-22-3 2-iodomethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 43041-12-9 methyl pyrrolidine-2-carboxylate 
• 182210-00-0 methyl (2R)-(benzyloxycarbonyl)pyrrolidine-2-carboxylate 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 
• 72597-18-3 (2R)-(+)-phenylmethyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 213014-28-9 2-(4-phenoxy-benzenesulfonylmethyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 213014-32-5 2-(4-phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-pyrrolidine-2-carboxylic acid 

Relevant articles and documents

An Efficient and Catalytically Enantioselective Route to (S)-(-)-Phenyloxirane

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Ketene Dithioacetals as 1,3-Dipolarophiles. Applications to the Synthesis of Cyclic Amino Acids

Intramolecular azide cycloaddition reactions of ketene dithioacetals provide a new route to cyclic amino acids and a stereoselective synthesis of (2S,3S,4R)-3,4-dihydroxyproline (14) based on this methodology is described.

HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES

The present invention provides a compound which is useful as a PGI2 receptor agonist, and a pharmaceutical composition. The present invention is directed to a pharmaceutical composition comprising a compound represented by the following formula [1]: (R1 and R2 are the same or different and each represents optionally substituted aryl, Y represents N or CH, Z represents N or CH, A represents NH, NR5, O, S, or ethylene, R5 represents alkyl, D represents alkylene or alkenylene, E represents phenylene or single bond, G represents O, S, or CH2, R3 and R4 are the same or different and each represents hydrogen or alkyl, Q represents carboxy, alkoxycarbonyl, tetrazolyl, carbamoyl, or N-(alkylsulfonyl)carbamoyl), or a pharmaceutically acceptable salt thereof as an active ingredient.

Ketene-S,S-Acetals As 1,3-Dipolarophiles Towards Azides. A New Synthetic Entry Into Cyclic Amino Acids

Intramolecular azide cycloaddition reactions of ketene-S,S-acetals proceed to give a reactive imine as the initially-formed intermediate and this mechanism is supported by thermolysis of (18) which gave the stable imine (22).N-Acylation of this intermedia