1086703-22-1

Basic information

• Product Name: C₂₉H₄₇N₃O₆
• Synonyms: C₂₉H₄₇N₃O₆
• CAS NO: 1086703-22-1
• Molecular Weight: 533.709
• Mol File: 1086703-22-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₉H₄₇N₃O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₄₇N₃O₆(1086703-22-1)
• EPA Substance Registry System: C₂₉H₄₇N₃O₆(1086703-22-1)

Safety Data

• Hazardous Substances Data: 1086703-22-1(Hazardous Substances Data)

Upstream product

• 1004524-62-2 10-Methyl-undecanoyl chloride 
• 2724-56-3 isolauric acid 
• 1086703-19-6 C₂₂H₃₃N₃O₇ 

Downstream Products

• 1086703-24-3 C₂₈H₄₅N₃O₆ 

Relevant articles and documents

Intramolecular suzuki-miyaura reaction for the total synthesis of signal peptidase inhibitors, arylomycins A2and B2

Development of the total syntheses of arylomycins A1 and B 2 is detailed. Key features of our approach include 1) formation of 14-membered meta, meta-cyclophane by an intramolecular Suzuki-Miyaura reaction; 2) incorporation of N-Me-4-hydroxyphenylglycine into the cyclization precursor, which avoids the late-stage low-yielding N-methylation step; 3) segment coupling of a fully elaborated peptide side chain to the macrocycle, which makes the synthesis highly convergent. Overall, arylomycin A2 was obtained in 13 steps from L-Tyr for the longest linear sequence, in 13% overall yield. Arylomycin B2 was synthesized in 10 steps from L-3-nitro-Tyr, in 10% overall yield.