1087243-27-3Relevant articles and documents
Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors
Ghosh, Arun K.,Gong, Gangli,Grum-Tokars, Valerie,Mulhearn, Debbie C.,Baker, Susan C.,Coughlin, Melissa,Prabhakar, Bellur S.,Sleeman, Katrina,Johnson, Michael E.,Mesecar, Andrew D.
, p. 5684 - 5688 (2008)
Design, synthesis and biological evaluation of a series of 5-chloropyridine ester-derived severe acute respiratory syndrome-coronavirus chymotrypsin-like protease inhibitors is described. Position of the carboxylate functionality is critical to potency. I
