108783-63-7Relevant articles and documents
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment
Ammirati, Mark,Bagley, Scott W.,Bhattacharya, Samit K.,Buckbinder, Leonard,Carlo, Anthony A.,Conrad, Rebecca,Cortes, Christian,Dow, Robert L.,Dowling, Matthew S.,El-Kattan, Ayman,Ford, Kristen,Guimar?es, Cristiano R. W.,Hepworth, David,Jiao, Wenhua,Laperle, Jennifer,Liu, Shenping,Londregan, Allyn,Loria, Paula M.,Mathiowetz, Alan M.,Munchhof, Michael,Orr, Suvi T. M.,Petersen, Donna N.,Price, David A.,Skoura, Athanasia,Smith, Aaron C.,Wang, Jian
supporting information, p. 1128 - 1133 (2015/11/24)
Recent studies in adipose tissue, pancreas, muscle, and macrophages suggest that MAP4K4, a serine/threonine protein kinase may be a viable target for antidiabetic drugs. As part of the evaluation of MAP4K4 as a novel antidiabetic target, a tool compound,
SYNTHESIS AND SPECTRAL AND LUMINESCENT PROPERTIES OF 4-(5-ARYLOXAZOYL-2)BENZOIC ACIDS AND THEIR DERIVATIVES
Krasovitskii, B. M.,Shershukov, V. M.,Volkov, V. L.
, p. 1022 - 1025 (2007/10/02)
Condensation of acid chloride of monomethyl terephtalate with ω-aminomethylarylketones and subsequent cyclodehydration of the resulting amides in sulfuric acid or phosphorus oxychloride give rise to methyl 4-(5-aryloxazolyl-2)benzoates which led to the co