1089186-95-7

Basic information

• Product Name: 1-(3-fluoro-4-hydroxy-5-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide
• Synonyms: 1-(3-fluoro-4-hydroxy-5-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide
• CAS NO: 1089186-95-7
• Molecular Weight: 341.164
• Mol File: 1089186-95-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-fluoro-4-hydroxy-5-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-fluoro-4-hydroxy-5-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide(1089186-95-7)
• EPA Substance Registry System: 1-(3-fluoro-4-hydroxy-5-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide(1089186-95-7)

Safety Data

• Hazardous Substances Data: 1089186-95-7(Hazardous Substances Data)

Upstream product

• 456-49-5 1-fluoro-3-methoxybenzene 
• 73943-41-6 2-fluoro-6-methoxyphenol 
• 103905-49-3 5-<(dimethylamino)methyl>-1-fluoro-2-hydroxy-3-methoxybenzene 
• 74-88-4 methyl iodide 

Downstream Products

• 1470111-21-7 C₄₂H₅₁FO₁₀Si 
• 1470111-29-5 C₃₆H₃₇FO₁₀ 
• 79418-78-3 3-fluoro-4-hydroxy-5-methoxybenzaldehyde 
• 1470110-64-5 formic acid 4-(tert-butyldimethylsilanyloxy)-3-fluoro-5-methoxyphenyl ester 
• 1470110-70-3 4-(tert-butyldimethylsilanyloxy)-3-fluoro-5-methoxyphenol 
• 71924-61-3 3-fluoro-4,5-dimethoxybenzaldehyde 
• 99424-78-9 3,4-dimethoxy-5-fluorophenethylamine 

Relevant articles and documents

Chemoselective zinc/HCl reduction of halogenated β-nitrostyrenes: Synthesis of halogenated dopamine analogues

A detailed account regarding the synthesis of 2- and 5-halogenated dopamine is given. The key step is a chemoselective reduction of a nitrostyrene by Zn/HCl at 0 °C. These conditions represent a simple, low-cost alternative to reduction by water-sensitive hydride donors and two-step procedures. Under these conditions, aryl fluoride, chloride, and bromide groups are stable. However, iodine undergoes significant reductive dehalogenation.