1089187-43-8

Basic information

• Product Name: 2-propyl-sulfonyl-N-(2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazino]-ethoxy}-benzofuran-5-yl)-amide
• Synonyms: 2-propyl-sulfonyl-N-(2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazino]-ethoxy}-benzofuran-5-yl)-amide
• CAS NO: 1089187-43-8
• Molecular Weight: 571.661
• Mol File: 1089187-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-propyl-sulfonyl-N-(2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazino]-ethoxy}-benzofuran-5-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propyl-sulfonyl-N-(2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazino]-ethoxy}-benzofuran-5-yl)-amide(1089187-43-8)
• EPA Substance Registry System: 2-propyl-sulfonyl-N-(2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazino]-ethoxy}-benzofuran-5-yl)-amide(1089187-43-8)

Safety Data

• Hazardous Substances Data: 1089187-43-8(Hazardous Substances Data)

Upstream product

• 1089187-68-7 2,2-dimethyl-5-nitro-7-{2-[4-(2-methoxy-5-trifluoro-methyl-phenyl)-piperazine-1-yl]-ethoxy}-2,3-dihydro-benzofuran 
• 1089187-62-1 2,2-dimethyl-5-nitro-7-(2-chloro-ethoxy)-2,3-dihydro-benzofuran 
• 113194-07-3 2,2-dimethyl-5-nitro-2,3-dihydro-benzofuran-7-ol 
• 10147-37-2 Isopropylsulfonyl chloride 
• 1089187-35-8 2,2-dimethyl-5-amino-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazin-1-yl]-ethoxy}-2,3-dihydro-benzofuran 

Relevant articles and documents

NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION

The present invention relates to new selective 5HT6 receptor binding benzofuran derivatives of general formula (I) wherein, Z represents a hydrogen atom, C1-4 acyl group, C1-6 alkyl sulfonyl group, phenyl sulfonyl group substituted with one or more halogen atom; or naphthyl sulfonyl group optionally substituted with a halogen atom, tetrahydro naphthyl sulfonyl group, (lS)(+)-10-camphor-sulfonyl group, (lR)(-)-10-camphor-sulfonyl group or benzofuranyl sulfonyl group, substituted with a halogen atom and C1 -4 alkyl group, Y represents C2-6 alkylene group, R1 and R2 represent, independently, a hydrogen atom, C1-4 alkyl group, benzyl group, or together with one or more halogen atoms, trifluoromethyl group, or C1-4 alkoxy group substituted 4-phenyl-piperazine-l-yl group; and/or their pharmaceutically suitable acid addition salts, to the process for producing said compounds, to pharmaceutical compositions containing said compounds and to their use in treatment and/or prevention of disorders of the central nervous system and cardiovascular system.