108919-91-1

Basic information

• Product Name: 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide
• Synonyms: 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide
• CAS NO: 108919-91-1
• Molecular Weight: 258.319
• Mol File: 108919-91-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide(108919-91-1)
• EPA Substance Registry System: 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide(108919-91-1)

Safety Data

• Hazardous Substances Data: 108919-91-1(Hazardous Substances Data)

Upstream product

• 53336-42-8 3-bromo-2,3-dihydro-thiophene-1,1-dioxide 
• 873-55-2 sodium benzenesulfonate 
• 64741-13-5 3-thiophenyl-3-sulfolene 
• 7326-61-6 3-Chlor-4-phenylmercapto-tetrahydro-thiophen-1.1-dioxid 
• 931-59-9 benzenesulfenyl chloride 
• 7311-84-4 trans-3,4-dibromosulfolane 

Downstream Products

• 114597-07-8 4,7-dihydro-1-isopropylidene-6-(phenylsulfonyl)indene 
• 114596-93-9 4-(phenylsulfonyl)-4-vinyl-2-cyclohexenone 
• 114596-92-8 3-methoxy-4-(phenylsulfonyl)-4-vinylcyclohexanone 
• 127844-19-3 3-Benzenesulfonyl-3-benzyl-2,3-dihydro-thiophene 1,1-dioxide 
• 114596-96-2 4,7-dihydro-6-(phenylsulfonyl)indene 
• 127844-20-6 3-Benzenesulfonyl-3-ethyl-2,3-dihydro-thiophene 1,1-dioxide 
• 114597-01-2 5-endo-(phenylsulfonyl)-5-exo-vinylbicyclo<2.2.2>-2-octene 
• 114597-00-1 1,4,7,8,9,10-hexahydro-2-(phenylsulfonyl)naphthalene 
• 114597-08-9 1,4,5,8,9,10-hexahydro-1,4-methano-7-(phenylsulfonyl)naphthalene 
• 114597-03-4 1,2-dimethyl-4-(phenylsulfonyl)-4-vinylcyclohexene 
• 114597-04-5 4-isopropenyl-4-methyl-1-(phenylsulfonyl)cyclohexene 
• 123559-84-2 2-Methyl-3-(phenylsulfonyl)-2,5-dihydrothiophene 1,1 dioxide 
• 123559-85-3 2-Methyl-3-(phenylsulfonyl)-2,3-dihydrothiophene 1,1 dioxide 
• 218628-86-5 3,5-Dihydro-1H-thieno[3,4-c]pyrrolcarbonsaeure-benzylester 

Relevant articles and documents

Vinyl sulfones in solid-phase synthesis: Preparation of 4,5,6,7-tetrahydroisoindole derivatives

The preparation of functionalized 4,5,6,7-tetrahydroisoindole via a traceless solid-phase sulfone linker strategy is described. Thermolytic extrusion of SO2 from polymer-bound 3-(phenylsulfonyl)-3-sulfolene (7) generated polymer-bound 2-(phenylsulfonyl)-1,3-butadiene (9) in situ which underwent Diels-Alder cycloaddition with various dienophiles to furnish vinyl sulfone resins 10-14. To complete a traceless linker cleavage strategy, (p-tolysulfonyl)methyl isocyanide or ethyl isocyanoacetate was employed to react with the vinyl sulfone moiety to liberate functionalized 4,5,6,7-tetrahydroisoindole products from the resin. Using this chemistry, nine tetrahydroisoindole derivatives (6, 15-22) were prepared in 32-41% overall yields from polystyrene/divinylbenzene sulfinate 1.

An expedient synthesis of substituted tetraaryltetrabenzoporphyrins

A simple route to tetraaryltetrabenzoporphyrins (Ar4TBPs) is developed; the procedure allows for the introduction of substituents on both benzo- and phenyl-rings and employs readily available, inexpensive components.

4-Bromo-2-sulfolenes. Butadienyl Cation Equivalents

4-Bromo-2-sulfolene and 4-bromo-3-methyl-2-sulfolene react with alkylcuprates to give direct substitution products, with vinyl- or phenylcuprates or sulfur-containing nucleophiles to give allylic substitution products, and with strongly basic nucleophiles to give elimination products.The allylic substitution products and the isomerized direct substitution products are precursors for substituted 1,3-butadienes.Thus, these 4-bromo-2-sulfolenes serve as butadienyl cation equivalents.