108932-40-7Relevant articles and documents
Methods and Compositions to Inhibit Edema Factor and Adenylyl Cyclase
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, (2009/04/24)
Small molecules and their derivatives are described for the treatment and/or prevention of intestinal fluid loss. Also disclosed are methods of using said molecules and their derivatives to treat and/or prevent conditions associated with increased levels
Two methods for the preparation of 2-cyclohexenones from resin-bound 1,3-cyclohexanedione
Fraley, Mark E.,Rubino, Robert S.
, p. 3365 - 3368 (2007/10/03)
The addition of organolithium or Grignard reagents to viny]ogous ester resin 1 followed by mild hydrolysis of product resins 2 provides 3-alkyl-2-cyclohexenones in high purity (>95%). Alternatively, conversion of 1 to vinyl triflate resin 4 followed by palladium-mediated couplings with aryl boronic acids and hydrolysis furnishes 3-ary]-2-cyclohexenones in lower yield, but exceptional purity.