108981-97-1

Basic information

• Product Name: benzyl 4-oxo-4H-chromene-2-carboxylate
• Synonyms: benzyl 4-oxo-4H-chromene-2-carboxylate
• CAS NO: 108981-97-1
• Molecular Formula: C₁₇H₁₂O₄
• Molecular Weight: 280.27478
• Mol File: 108981-97-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: benzyl 4-oxo-4H-chromene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 4-oxo-4H-chromene-2-carboxylate(108981-97-1)
• EPA Substance Registry System: benzyl 4-oxo-4H-chromene-2-carboxylate(108981-97-1)

Safety Data

• Hazardous Substances Data: 108981-97-1(Hazardous Substances Data)

Upstream product

• 4940-39-0 acide chromone carboxylique-2 
• 100-51-6 benzyl alcohol 
• 118-93-4 o-hydroxyacetophenone 
• 37976-44-6 dibenzylacetylene dicarboxylate 
• 108-95-2 phenol 

Relevant articles and documents

SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A

Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

Acaricidal activity of tonka bean extracts. Synthesis and structure-activity relationships of bioactive derivatives

The acaricidal effects of tonka bean, Dipterix odorata, extracts were investigated on Dermatophagoides pteronyssinus, the European house dust mite, and compared with benzyl benzoate as a standard acaricidal compound. A cyclohexane extract was the most effective, with an EC50 = 0.075 g/m2 after a 24 h period, as compared with benzyl benzoate (0.025 g/m2). Bioassay-guided fractionation of this extract led to the isolation of coumarin (1). Pharmacomodulation of this compound led us to test 20 analogues (2-21), which were either synthesized or purchased.