1090-65-9

Basic information

• Product Name: 2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one
• Synonyms: ALPINETIN;2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one;7-Hydroxy-5-Methoxy-2-phenylchroMan-4-one
• CAS NO: 1090-65-9
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.28
• Mol File: 1090-65-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 225 °C
• Boiling Point: 494.9 °C at 760 mmHg
• Flash Point: 188.8 °C
• Appearance: /
• Density: 1.284 g/cm³
• Vapor Pressure: 2.03E-10mmHg at 25°C
• Refractive Index: 1.612
• PKA: 7.34±0.40(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one(1090-65-9)
• EPA Substance Registry System: 2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one(1090-65-9)

Safety Data

• Hazardous Substances Data: 1090-65-9(Hazardous Substances Data)

Usage

Description

2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one, also known as Alpinetin, is a naturally occurring compound with significant therapeutic potential. It is characterized by its unique chemical structure, which includes a benzopyran-4-one core, a phenyl group, and hydroxy and methoxy substituents. These features contribute to its diverse range of biological activities, making it a promising candidate for various applications in the pharmaceutical and healthcare industries.

Uses

Used in Pharmaceutical Industry:
2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one is used as a UCK2 inhibitor for its potential therapeutic applications. As a natural compound, it has been identified to possess inhibitory effects on uridine-cytidine kinase 2, an enzyme involved in the regulation of nucleotide metabolism. This property makes it a promising candidate for the development of novel therapeutic agents targeting various diseases.
Used in Antimicrobial Applications:
2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one is used as an antimicrobial agent due to its ability to inhibit the growth of certain bacteria. Its unique chemical structure allows it to interfere with bacterial cell processes, making it a potential candidate for the development of new antibiotics to combat drug-resistant bacterial strains.
Used in Antitumor Applications:
2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one is used as an antitumor agent for its potential to inhibit the growth and proliferation of cancer cells. Its ability to target specific cellular pathways and mechanisms involved in tumor development and progression makes it a promising candidate for the development of novel anticancer drugs.

InChI:InChI=1/C16H14O4/c1-19-14-7-11(17)8-15-16(14)12(18)9-13(20-15)10-5-3-2-4-6-10/h2-8,13,17H,9H2,1H3

Upstream product

• 19309-14-9 cardamomin 

Downstream Products

• 76444-56-9 Uvangoletin 
• 1036-72-2 5,7-dimethoxyflavone 

Relevant articles and documents

Constituents of Boesenbergia pandurata ( syn. Kaempferia pandurata) : Isolation, Crystal Structure and Synthesis of (+/-)-Boesenbergin A

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