109000-07-9

Basic information

• Product Name: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-[(4-methylphenyl)sulfonyl]-
• CAS NO: 109000-07-9
• Molecular Formula: C13H13NO3S
• Molecular Weight: 263.317
• Mol File: 109000-07-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-[(4-methylphenyl)sulfonyl]-(109000-07-9)
• EPA Substance Registry System: 2-Azabicyclo[2.2.1]hept-5-en-3-one, 2-[(4-methylphenyl)sulfonyl]-(109000-07-9)

Safety Data

• Hazardous Substances Data: 109000-07-9(Hazardous Substances Data)

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 18964-33-5 2-(toluene-4-sulfonyl)-2-aza-bicyclo[2.2.1]heptan-3-one 
• 124575-13-9 cis-4-p-toluenesulfonylaminocyclopent-2-enylmethanol 
• 124575-15-1 N-((1R,3S)-3-Hydroxymethyl-cyclopentyl)-4-methyl-benzenesulfonamide 
• 118353-05-2 cis-<4-(hydroxymethyl)-2-cyclopentenyl>guanine 
• 141765-45-9 5-endo-chloro-6-exo-phenylsulfenyl-2-(p-tolylsulfonyl)-2-azabicyclo<2.2.1>heptan-3-one 
• 141765-46-0 5-endo-bromo-6-exo-phenylselenyl-2-(p-tolylsulfonyl)-2-azabicyclo<2.2.1>heptan-3-one 
• 141765-46-0 5-exo-bromo-6-endo-phenylselenyl-2-(p-tolylsulfonyl)-2-azabicyclo<2.2.1>heptan-3-one 

Relevant articles and documents

π-Allylpalladium formation from allylic amines via N,N-ditosylimides and N-tosylamides: Efficient synthesis of the antiviral agent carbovir

Allylic amines can be easily converted into their N,N-ditosylimides or N-tosylamides which are sufficiently good leaving groups to afford π-allylpalladium complexes and, hence, with nucleophiles, new allylic systems with retention of configuration. The synthetic utility of this process has been demonstrated by an efficient synthesis of the antiviral agent (±)-carbovir (1) from cyclopentadiene in only seven steps and 13% overall yield.

Synthesis of carbocyclic nucleosides from 2-azabicyclo[2.2.1]hept-5-en-3-ones: Sodium borohydride-mediated carbon-nitrogen bond cleavage of five- and six-membered lactams

Various carbocyclic ribofuranosyl nucleosides were stereoselectively synthesized through a small number of steps from 2-azabicyclo[2.2.1]hept-5-en-3-ones by the use of sodium borohydride-mediated C-N bond cleavage as a key step. Ready availability of a no